Proteomics of Human Body Fluids

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Rapid growth of the "proteomics" field during the past twelve years has c- tributed to significant advances in science. To date, proteomic technologies have been widely applied to examining various kinds of biological materials. Clinical proteomics …
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    Om Proteomics of Human Body Fluids

    Rapid growth of the "proteomics" field during the past twelve years has c- tributed to significant advances in science. To date, proteomic technologies have been widely applied to examining various kinds of biological materials. Clinical proteomics is the concept of using proteomic techniques to evaluate the proteomes in clinical samples for biomarker discovery and for better understa- ing of normal physiology and pathogenic mechanisms of human diseases. Tra- lating the proteomic information to clinical practice may lead to the ultimate goals of earlier diagnosis, improved therapeutic outcome and successful prev- tion of diseases. Human body fluids are produced, secreted, and/or excreted from various tissues or organs. Major compositions of body fluids are water, organic s- stances and inorganic compounds. These compositions vary in each body fluid, making one's function different from the others. Analyses of protein com- nents in individual fluids would increase current knowledge on the biology and physiology of various organ systems, and on the pathophysiology of diseases, which cause alterations in protein production, secretion, and/or excretion from the affected tissues or organs into the body fluids. Additionally, human body fluids are the main targets and valuable sources for biomarker discovery. As the high-throughput capability and applicability of proteomics for analyzing proteins in the body fluids have been already proven, these desires are most likely achievable by using proteomic technologies.

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    Format
    E-Bok
    Kopisperre
    Teknisk DRM
    Filformat
    PDF
    Utgivelsesår
    2008
    Forlag
    Humana Press
    Språk
    Engelsk
    ISBN
    9781597454322

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