|Forlag||World Scientific Publishing Co|
|Emne||Computer science; Life sciences: general issues; Molecular biology|
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Om Lecture Notes on Computational Structura
While the field of computational structural biology or structural bioinformatics is rapidly developing, there are few books with a relatively complete coverage of such diverse research subjects studied in the field as X-ray crystallography computing, NMR structure determination, potential energy minimization, dynamics simulation, and knowledge-based modeling. This book helps fill the gap by providing such a survey on all the related subjects. Comprising a collection of lecture notes for a computational structural biology course for the Program on Bioinformatics and Computational Biology at Iowa State University, the book is in essence a comprehensive summary of computational structural biology based on the author's own extensive research experience, and a review of the subject from the perspective of a computer scientist or applied mathematician. Readers will gain a deeper appreciation of the biological importance and mathematical novelty of the research in the field.Contents:X-ray Crystallography ComputingNMR Structure DeterminationPotential Energy MinimizationMolecular Dynamics SimulationKnowledge-based Protein ModelingAppendices:Design and Analysis of Computer AlgorithmsNumerical MethodsReadership: Academics and graduate students in the bioinformatics and computational biology field, as well as those involved in related industrial research and development.