Fluorescent materials are revolutionizing science and industry with their remarkable photophysical properties and versatile applications in bioimaging, diagnostics, and beyond. Despite their promise, traditional fluorophores often face limitations due to aggregation-caused quenching (ACQ) effects, which diminish their fluorescence in solid-state or aggregated forms. The ground breaking phenomenon of aggregation-induced emission (AIE), first reported by Professor Ben Zhong Tang and colleagues in 2001, overcame this challenge. AIE-active molecules uniquely enhance fluorescence in solid or aggregated states, thanks to restricted intramolecular motion (RIM). This discovery has sparked a wave of advancements, leading to diverse applications in fluorescence sensing, diagnostics, and imaging. This edited volume brings together chapters from renowned researchers worldwide, showcasing the latest progress in sensing applications of AIE luminogens. With comprehensive and up-to-date coverage, it serves as an invaluable resource for professionals in fluorescence-based analytical and detection work. Whether you're exploring bioimaging or developing fluorescent devices, this book offers essential insights to advance your work. An indispensable reference for academics, students, and industry professionals, this book opens the door to the transformative possibilities of AIE luminogens.