This is the fifth volume of the series, highlighting research in the field of animal cell technology. Recent data on cell growth and productivity in various cell culture systems are provided, including systems for recombinant animal gene expression and production of monoclonal antibodies, extending the investigations in the previous volumes. In addition, application of cell culture systems in new areas are presented: biosafety testing, removal of microorganisms, and the assessment of physiologically functional substances in food and natural sources. Also, a special section deals with applications of human monoclonal antibodies. All those involved in animal cell culture should find this volume a useful source on current research.