This book is a unique synthesis of the major concepts and methods in bacterial population genetics in infectious disease, a field that is now about 35 yrs old.  Emphasis is given to explaining population-level processes that shape genetic variation in bacterial populations and statistical methods of analysis of bacterial genetic data. A "how to" of bacterial population genetics, which covers an extremely large range of organismsExpanding area of science due to high-throughput genome sequencing of bacterial pathogensCovers both fundamental approaches to analyzing bacterial population structures with conceptual background in bacterial population biologyDetailed treatment of statistical methods