This book explores whether humans should continue leading or allow AI, with its growing capabilities, to take prominent leadership roles. The author addresses the practical and ethical dimensions, vital for understanding AI's role in our future society. The book provides a thoughtful analysis of leadership roles in the age of AI and insights into AI’s societal impacts, ethical challenges, and how humans and AI can responsibly coexist and co-lead. The book uniquely integrates firsthand global policy-making experience, notably contributing to UNESCO’s widely adopted AI ethics framework. The author emphasizes practical implementation, ethical considerations, and offers balanced insights for diverse readers.