Since the first moment of conquest, colonizers and the colonized alike in Mexico confronted questions about what it meant to be from this place, what natural resources it offered, and who had the right to control those resources and on what basis. Focusing on the ways people, environment, and policies have been affected by political boundaries, historian Rick A. López explores the historical connections between political identities and the natural world. López analyzes how scientific intellectuals laid claim to nature within Mexico, first on behalf of the Spanish Empire and then in the name of the republic, during three transformative moments: the Hernández expedition of the late sixteenth century; the Royal Botanical Expedition of the late eighteenth century; and the heyday of scientific societies such as the Sociedad Mexicana de Historia Natural of the late nineteenth century. This work traces how scientific intellectuals studied and debated what it meant to know and claim the flora that sprang from Mexican soil—ranging from individual plants to forests and vegetated landscapes—and the importance they placed on indigeneity. It also points to the short- and long-term consequences of these efforts. López draws on archival and published sources produced from the sixteenth century through the start of the twentieth century and gives special attention to the use of visual images such as scientific illustrations and landscape art. López employs the term “visualization” in recognition of the degree to which officials, botanists, and draftsmen produced imagery and also how they and others viewed nature. Rooted in Place reveals how scientific endeavors were not just about cataloging flora but were deeply intertwined with the construction of identity and the political landscape at three pivotal moments in Mexican history.