The way we design and build our cities, buildings, and public spaces takes on critical importance in the face of critical issues such as climate change, social inequality, and rapid urbanization. Architecture and design not only shape the environments in which we live but also influence energy use, natural resource management, and social inclusion. These disciplines have the potential to play a pivotal role in advancing sustainable development, yet their contributions are often overlooked. Sustainability, Resilience, and Inclusiveness through Human-Centred Architecture and Design examines the profound ways in which architecture and design can contribute to global imperatives framed by the United Nations Sustainable Development Goals (SDGs), particularly those focused on sustainable cities and communities (SDG 11), affordable and clean energy (SDG 7), and reduced inequalities (SDG 10). This volume offers a three-part exploration. Part 1 delves into energy efficiency, discussing innovations like biomimicry for zero-energy buildings and IoT-integrated systems in educational spaces. Part 2 bridges sustainability and heritage preservation, showcasing AI-assisted designs and adaptive placemaking strategies. Finally, Part 3 presents real-world case studies, from Saudi Arabia’s sustainable design frameworks to the impact of the pandemic on residential spaces in Egypt. With fresh insights and empirical evidence, this collected edition sets a new agenda for integrating human-centered approaches into sustainable design and architecture. Providing a vital resource for academics, policymakers, architects, and urban planners, Human-Centered Architecture and Design underscores the urgent need for collaboration across disciplines to create a built environment that supports thriving, resilient, and inclusive communities.