Preface.- Part 1. Analyses of the Responsibility of Science.- 1. Responsibility in Science: The Philosophical View (Hans Lenk).- 2. Science as a Profession and its Responsibility (Harald A. Mieg).- 3. Corporate Responsibility: A Principle of Responsive Adjustment (Peter A. French).- Part 2. The Social Sciences View: Structural Conditions for Science Responsibility.- 4. Science Policy: From the Linear Model to Responsible Research and Innovation (Philip Macnaghten).- 5. European Law: The Precautionary Principle and Science-based Innovation in Europe (Ellen Vos & Kristel de Smedt).- 6. History of Science: Ambivalence(s) in the Research and use of Nuclear Energy (Horst Kant).- Part 3. The Scientists' Voice on the Responsibility of Science.- 7. Between Parrhesia and Fake: Scientific Responsibility Today (Rainer E. Zimmermann).- 8. On the Responsibility of Science for Guaranteeing Human Rights: In the Fight Against Human Degradation, Racism, and Anti-Semitism (Klaus Fuchs-Kittowski).- 9. The Ambivalences of the Digital: Humans and Technologies Between new Options (dreams) and (un)noticeable Losses (Hartmut Graßl et al.)- Index.