This book presents the proceedings of the 11th Conference on Theory and Applications of Soft Computing, Computing with Words and Perceptions and Artificial Intelligence, ICSCCW-2021, held in Antalya, Turkey, on August 23–24, 2021. The general scope of the book covers uncertain computation, decision making under imperfect information, neuro-fuzzy approaches, natural language processing, and other areas. The topics of the papers include theory and application of soft computing, computing with words, image processing with soft computing, intelligent control, machine learning, fuzzy logic in data mining, soft computing in business, economics, engineering, material sciences, biomedical engineering, and health care. This book is a useful guide for academics, practitioners, and graduates in fields of soft computing and computing with words. It allows for increasing of interest in development and applying of these paradigms in various real-life fields.