This book presents cutting-edge research and developments in the field of biomedical engineering, with a special emphasis on achievements by Asian research groups. It covers machine learning and computational modeling methods applied to biomedical and clinical research, advanced methods for biosignal processing and bioimaging, MEMS applications, and advances in biosensors. Further topics include biomechanics, prosthetics, orthotics and tissue engineering. Other related (bio-) engineering applications, such as in ecosystem development, water quality assessment, and material research, are also covered. Gathering the proceedings of the 6th Kuala Lumpur International Conference on Biomedical Engineering, held online on July 28-29, 2021 from Kuala Lumpur, Malaysia, the book is intended to provide researchers and professionals with extensive and timely information on the state-of-the-art research and applications in biomedical engineering, and to promote interdisciplinary and international collaborations.