Written by a Clinical Nurse Specialist for Clinical Nurse Specialists, this text explores the expanding roles and responsibilities of the CNS- from core competencies and theoretical foundations for practice to caring for the hospitalized adult to shaping the healthcare system through the CNS's spheres of influence. With a special emphasis on the practical application in clinical practice the author uses a body-system approach to guide readers through evidence-based collaborative and independent nursing interventions within the framework of the CNS role.