AHFS Drug Information® 2026 contains the most dependable drug information available—all in one place. It is the most comprehensive evidence-based source of drug information complete with therapeutic guidelines and off-label uses. With expanded and revised content supported by more than 97,000 references and incorporating the advice of numerous subject matter experts, AHFS DI helps you protect your patients and your practice. Updates in the new edition:Clinical perspective sections that include place of therapy discussions and recommendations from therapeutic guidelinesExpanded coverage of specialty medications used to treat a variety of complex, chronic conditions that often require special handling and administration and may require careful oversight to manage severe adverse effects and dosage adjustmentsContemporary topics such as biosimilars, novel orphan drugs, and updated vaccine guidance based on recommendations from the CDC’s Advisory Committee on Immunization Practices (ACIP) and other authoritative organizationsEssential drug information content for patient safety including FDA Medwatch alerts, Standardize4Safety concentrations for IV and oral liquid medications, ISMP recommendations, REMS data, BEERS criteria, boxed warnings, and focused updates based on FDA safety findingsPharmacogenomic considerations in drug dosing and selectionExpanded content on new and emerging gene and cellular therapiesClass-wide revisions to standard and established therapies for common disease states including hypertension and diabetesExpanded content on off-label uses, real world data, and long-term clinical dataNew content on new molecular entities (NMEs) and biologic approvalsNew oncology off-label determinations based on reviews by the AHFS Oncology Expert Committee