Anatomy and physiology of lymphatic circulation.- Pathophysiology of lymphatic circulation in different disease conditions.- Methodological aspects of lymphoscintigraphy: radiopharmaceuticals and instrumentation.- Lymphoscintigraphy for the differential diagnosis of peripheral edemas.- Lymphoscintigraphy for the characterization of intracavitary lymph effusions.- The sentinel lymph node concept in oncologic surgery.- General concepts on radioguided sentinel lymph node biopsy: preoperative imaging, intraoperative gamma-probe guidance, intraoperative imaging, multimodality imaging.- SPECT/CT image generation and criteria of interpretation for sentinel lymph node mapping.- Preoperative and intraoperative lymphatic mapping for radioguided sentinel node biopsy in breast cancer.- Preoperative and intraoperative lymphatic mapping for radioguided sentinel node biopsy in cutaneous melanoma.- Preoperative and intraoperative lymphatic mapping for radioguided sentinel node biopsy in head and neck cancers.- Preoperative and intraoperative lymphatic mapping for radioguided sentinel node biopsy in non-small-cell lung cancer.- Preoperative and intraoperative lymphatic mapping for radioguided sentinel node biopsy in cancers of the gastrointestinal tract.- Preoperative and intraoperative lymphatic mapping for radioguided sentinel node biopsy in cancers of the female reproductive system.- Preoperative and intraoperative lymphatic mapping for radioguided sentinel node biopsy in cancers of the male reproductive system.- Preoperative and intraoperative lymphatic mapping for radioguided sentinel node biopsy in kidney and bladder cancers.