A comprehensive survey by leading basic and clinical researchers of the signal transduction mechanisms responsible for lung inflammation, including vascular hyperpermeability, white cell accumulation, and vascular remodeling. The authors cut across disciplines to bring together a broad-based presentation of inflammatory challenge, both in the initial phases of the inflammatory response, as well as in the more prolonged phase of genomic involvement. The book illuminates not only the processes of lung inflammation, but also the potential for developing new therapeutic strategies to combat inflammatory lung disease.