In the face of enduring global inequalities and colonial legacies, social scientists in the Anglo-Caribbean navigate complex challenges in their research and career-making. This book reveals how academics in the Global South negotiate global asymmetries in their daily work. Through fieldwork and interviews with senior scholars, the author explores how Anglo-Caribbean social scientists creatively work towards a regional science system. The book emphasizes the creativity and collective action of scholarly communities. This work is essential for rethinking global entanglements in academia and working towards critical perspectives on social science knowledge production.