This book aims to provide the reader with an in-depth overview of the diagnostic and therapeutic options currently available in epilepsy surgery. It juxtaposes diagnostic methods and surgical techniques that have existed for a long time and others that have recently been developed or have gained importance. The nuanced comparison shows that several methods may be applicable for the same indication but, depending on the specific circumstances, one of them may be the best choice. The book is divided into four main parts, focusing on anatomy, pre-surgical diagnostic evaluation of epilepsy, curative surgical treatment of epilepsy and symptomatic surgical treatment of epilepsy. The chapters are designed to describe not only a method or technique but also their specific risks or the limits where the competing option may become preferable. The book thus guides the readers through the current controversies and helps them make a rational decision for their patients. It will be a valuable resource for neurosurgeons, neurologists,neurophysiologists, neuroradiologists and neuropsychologists dedicated to the treatment of drug-resistant epilepsy and for the multidisciplinary epilepsy surgery conferences.