Data-driven analytics is enjoying unprecedented popularity among oil and gas professionals. A large number of reservoir engineering problems associated with geological storage of CO2 require development of numerical reservoir simulation models. The numerical models are used to understand the impact of injection of CO2 in saline aquifers, depleted oil and gas reservoirs, as well as CO2-EOR projects. This book discusses application of data-driven analytics to geological storage of CO2. It explains the technology that allows for uncertainty quantification and optimization of CO2 storage projects. It also deals with actual case studies from Australia and the United States.