Focusing on basic theory, emerged technologies and underlying engineering solutions, we investigate frontiers of engineering and science in design and control of physical and cyber-physical systems (CPS). Advanced-technology multi-physics systems are designed by seamlessly integrating components and modules, guaranteeing overall specifications and functionality by means of data processing, management and control. Analog and digital controllers and data management are implemented by analog and mixed-signal ASICs, as well as by microcontrollers and field-programmable gate arrays. Cybersecurity and information security have become critical. This book focuses on engineering solutions and covers frontiers of engineering and science. Basic theory, emerged technologies, advanced software, enabling hardware and computing environments are applied. Recent innovations and discoveries are reported. We demonstrate and apply underlying fundamentals in design of complex systems. This book aims to:Consistently cover topics on engineering science and engineering design pertaining to physical systems and their componentsEducate and assist one in development of problem-solving skills and design proficiencyEnsure in-depth pervasive presentation and consistent coverageEndow the end-user with adequate knowledge in engineering analysis and designThe emerged technologies and hardware have advanced system organization and enabled capabilities. The recent developments are empowered by new solutions. The major objective of this book is to empower concurrent design, as well as to enable a deep understanding of engineering underpinnings and integrated technologies. Key concepts and paradigms are covered.