This book essentially provides a refreshing description of the cortical and subcortical anatomy of the brain and how it relates to function. It includes subtleties of anatomy, advances in imaging, operative nuances, techniques, and a brief discussion about artificial intelligence. It discusses surgical strategies on intrinsic brain tumors in general and gliomas in particular with several images. The issues that need to be considered in decision-making are explained in this book. The best surgical options are described step-by-step. The relevant anatomy and function of the region are discussed and show the consequences of the damage. This book covers the intra-operative nuances to prevent neurological morbidity. Modern imaging features that help during surgery and decision-making are elaborated. The book is heavily illustrated with anatomical images, intraoperative images, radiologic images, and drawings supported by videos of the surgical approaches and techniques. The chapter structure involves reoccurring headings, didactic elements such as chapter summaries, boxes (note, caution), bullet points, tables, flowcharts, key points. This book is handy for neurosurgeons, especially neuro-oncologists, which helps keep them abreast with the advances in the field.