This book developed from the experience of the ISAMMS team (Institut Sud Aquitain de la Main et du Membre Superieur), that has been treating hand and wrist pathologies for over 20 years. Hand and wrist require specific care from a multidisciplinary staff. The patient has to be treated efficiently from injury in order to be able to return to work and sports activities. The book presents the most validated clinical examination, clinical reasoning, rehabilitation techniques and orthoses allowing the therapist to maximize their efficiency in treating patients with hand and wrist pathologies. This publication is intended for physiotherapists and occupational therapists, surgeons and practitioners specialized in physical rehabilitation, as well as for the students in these fields.