Hypercortisolism: Diagnosis and Differential Diagnosis, Volume 132 presents a comprehensive series of chapters focused on the various aspects of endogenous hypercortisolism as contributed by an international team of specialists in endocrinology. Chapters in this new release include Cushing´s syndrome: Clinical presentation and associated comorbidities, Biochemical diagnosis of hypercortisolism: when and how?, ACTH independent Cushing syndrome: diagnosis and etiology, Bilateral macronodular and micronodular hyperplasia: biochemical, radiological and genetic diagnosis, Differential diagnosis between endogenous Cushing´s syndrome and pseudoCushing, and much more. Additional chapters delve into Differential diagnosis of ACTH dependent Cushing´s syndrome: hormonal and radiological studies, Ectopic Cushing´s syndrome: clinical presentation and diagnosis, Cyclic Cushing´s syndrome, Mild autonomous cortisol secretion: diagnosis, Cushing´s syndrome and pregnancy: clinical presentation and diagnosis, Molecular profile of Cushing´s syndrome, Cardiometabolic comorbidities in overt Cushing´s syndrome, and New tools for the diagnosis of hypercortisolism.