This book constitutes the refereed proceedings of the 10th EAI International Conference on INISCOM 2024, held in Da Nang, Vietnam, during February 20–21, 2024. The 18 full papers included in this book were carefully reviewed and selected from 41 submissions. They were organized in topical sections as follows: industrial networks and intelligent systems; telecommunications systems and networks; information processing and data analysis; security and privacy.