In this book, it was researched whether differences in the formalization of management systems occur in certain countries and whether these can be attributed primarily to the culture of the country or whether there are other influences. A quantitative study was conducted in which the five factors Need for Instructions, Compliance with Instructions, Supervisor Support, Change Management, and Overformalization were surveyed and analysed with the cultural dimensions Power Distance and Uncertainty Avoidance according to Hofstede and GLOBE. The analysis has shown that the national culture has an influence on the formalization of management system measured by three of the five factors. Moreover, a correlation of the factor Overformalization with Hofstede’s UAI and a preference for centralization in high PD countries were identified. Although the differences in the formalization of the management system are not limited to cultural aspects, they are the only ones with high significance.