The three-volume set CCIS 1467, CCIS 1468, and CCIS 1469 constitutes the thoroughly refereed proceedings of the 7th International Conference on Life System Modeling and Simulation, LSMS 2021, and of the 7th International Conference on Intelligent Computing for Sustainable Energy and Environment, ICSEE 2021, held in Hangzhou, China, in October 2021. The 159 revised papers presented were carefully reviewed and selected from over 430 submissions. The papers of this volume are organized in topical sections on: Medical Imaging and Analysis Using Intelligence Computing; Biomedical signal processing, imaging, visualization and surgical robotics; Computational method in taxonomy study and neural dynamics; Intelligent medical apparatus, clinical applications and intelligent design of biochips; Power and Energy Systems; Computational Intelligence in Utilization of Clean and Renewable Energy Resources, and Intelligent Modelling, Control and Supervision for Energy Saving and Pollution Reduction; Intelligent Methods in Developing Electric Vehicles, Engines and Equipment; Intelligent Control Methods in Energy Infrastructure Development and Distributed Power Generation Systems; Intelligent Modeling, Simulation and Control of Power Electronics and Power Networks; Intelligent Techniques for Sustainable Energy and Green Built Environment, Water Treatment and Waste Management; Intelligent Robot and Simulation; Intelligent Data Processing, Analysis and Control in Complex Systems; Advanced Neural Network Theory and Algorithms; Advanced Computational Methods and Applications; Fuzzy, Neural, and Fuzzy-neuro Hybrids; Intelligent Modelling, Monitoring, and Control of Complex Nonlinear Systems; Intelligent manufacturing, autonomous systems, intelligent robotic systems; Computational Intelligence and Applications.