This proceedings of the International Congress and Workshop on Industrial AI 2021 encompasses and integrates the themes and topics of three conferences, eMaintenance, Condition Monitoring and Diagnostic Engineering management (COMADEM), and Advances in Reliability, Maintainability and Supportability (ARMS) into a single resource. The 21st century is witnessing the emerging extensive applications of Artificial Intelligence (AI) and Information Technologies (IT) in industry. Industrial Artificial Intelligence (IAI) integrates IT with Operational Technologies (OT) and Engineering Technologies (ET) to achieve operational excellence through enhanced analytics in operation and maintenance of industrial assets. This volume provides insight into opportunities and challenges caused by the implementation of AI in industries apart from future developments with special reference to operation and maintenance of industrial assets. Industry practitioners in the maintenance field as well as academics seeking applied research in maintenance will find this text useful.