This book explores the therapeutic potential of Lupeol, a naturally occurring triterpenoid. The introductory chapters present its physicochemical properties, chemical modifications, and synthetic analogs, highlighting its potential against various diseases. The beneficial effects of Lupeol are explored across a broad range of health conditions, including its role in skin diseases and cardioprotective effects. The book highlights its antioxidant, anti-inflammatory, and chemopreventive effects, including its use in nanoparticle formulations for enhanced efficacy. Its protective properties for the kidneys, liver, and brain are also explored, along with its ability to sensitize resistant cells to chemotherapy and radiation. The chapters discuss the antimicrobial, antiparasitic, and anti-cancer effects of Lupeol, its role in inhibiting tumor growth, angiogenesis, and metastasis, and its modulation of transcription factors involved in disease pathways. Traditional uses of Lupeol-containing plants in systems like Unani medicine and its influence on gut microbiota and postbiotics for disease management are examined. Towards the end, the book also addresses Lupeol's safety, toxicology, and future clinical potential. Key Features:Examines the therapeutic potential of Lupeol, a naturally occurring triterpenoid, through its diverse health applicationsPresents the physicochemical properties, chemical modifications, and synthetic analogs of LupeolHighlights the antioxidant, anti-inflammatory, and chemopreventive effects of Lupeol and its role in nanoparticle formulations for enhanced efficacy in cancer treatments. Explores the cardioprotective, nephroprotective, hepatoprotective, and neuroprotective properties of LupeolAddresses the safety, toxicology, and future clinical applications of LupeolIt is a useful resource for researchers and students in pharmaceutical sciences, ethnopharmacology, and traditional medicine.