Max Weber’s lecture ‘Science as a Vocation’ is a classic of social thought, in which central questions are posed about the nature of social and political thought and action. The lecture has often taken to be a summation of Weber’s thought. It can also be argued that, together with the responses of its admirers and critics, it provides a focus for discussion of the nature of modernity and its political consequences, and of the philosophical and political implications of the social or human sciences. This volume provides a full, clear, revised translation of the lecture, together with translations from the German of key contributions to the lively debate that followed its publication. The book concludes with a substantial essay on the current significance of the lecture, which discusses its relevance to the debates about the nature of science as a cultural phenomenon; the disjunction between science and nature; Weber’s conception of the disenchantment of the world; the division of scientific labour; and the fundamental nature and place of sociology.