The decision to develop a nuclear power programme is a significant undertaking by any country. In preparing the necessary nuclear power infrastructure, there are numerous activities that must be completed in a timely manner in line with the objectives of the nuclear power programme. This publication defines three milestones in the development of the infrastructure necessary for introducing nuclear power and provides guidance on the activities that need to be carried out before each milestone. This new revision incorporates the experiences and feedback from several countries which have already completed or progressed significantly in all three phases. It also includes an annex for outlining the specific infrastructure considerations for Small Modular Reactors, which are expected to be deployed in a number of countries in the coming years. This publication is principally for decision-makers, advisers and senior managers in government, utilities and regulatory bodies in Member States interested in introducing nuclear power.