In this issue of Critical Care Clinics, guest editors Drs. Lori Shutter and Deepa Malaiyandi bring their considerable expertise to the topic of Neurocritical Care, a rapidly growing specialty of complex care. Top experts in the field provide up-to-date articles on important clinical trials and evidence-based care of the critically ill patient with neurological injury. Contains 16 practice-oriented topics including current management of acute ischemic stroke; status epilepticus: a neurological emergency; neurotrauma and ICP management; neuropharmacology in the ICU; artificial intelligence and big data science in neurocritical care; and more.  Provides in-depth clinical reviews on neurocritical care, offering actionable insights for clinical practice.  Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.