This book, for the first time, proposes the complex systems management theory based on the integration of complex systems theory and management science to solve the overall complexity problem that cannot be dealt with by the reductionism approach. This theory not only provides a new way of thinking, but also introduces a novel logic for cognition, which has significant academic novelty and practical implications. In particular, by illustrating many real cases, it explains how to apply the complex systems management theory and contribute to practice. This book aims to build complex system management as a new integrated and fundamental concept in the field of management science that has significant potential, which has clear and important academic connotations. It develops a big-data-driven modeling technique for complex system scenarios based on the latest information technology to improve the ability of complex systems management theory in coping with the complexity of real problems. This book provides a new paradigm of thinking, a body of knowledge, and management tools for scholars and practitioners to analyze and solve problems with complex integrity.