This book offers an essential guide to managing the most-debated hot topics of practical interest in anesthesia and intensive care. Part I reviews the state of the art in issues concerning both intensive care medicine and anesthesia, such as perioperative medicine, acute liver failure, anesthesia monitoring and ERAS in hepatic surgery. Part II focuses on microbiome in critically ill patients, on COVID-19 aspects and related issues, on sepsis in pediatric patients and ventilatory management in obese patients. Written by leading experts and including updated references, it provides a comprehensive, easy-to-follow update on anesthesia and intensive care. The book clearly explains complex topics, offering practicing clinicians valuable insights into the latest recommendations and evidence in the field while, at the same time, making it a vital resource for students new to the fields of anesthesia and intensive care.