This book gathers the peer-reviewed papers presented at the 19th Iberian Conference on Information Systems and Technologies (CISTI’2024), held at the University of Salamanca, Spain, from June 25 to 28, 2024. CISTI is a leading international forum that brings together academics, researchers, practitioners, and industry professionals to exchange insights on the latest advances and applications of information systems and technologies. The conference highlights not only cutting-edge research but also practical case studies, bridging the gap between theoretical innovation and real-world implementation. The contributions span a wide range of thematic areas, including organizational models, knowledge management, software engineering, networks and mobility, human-centered computing, health informatics, educational technologies, and construction engineering. This book offers a reliable reference for researchers and postgraduate students, while also serving as a practical resource for professionals and decision-makers seeking to harness digital technologies to address organizational, educational, and societal challenges. It reflects the role of information systems as a key driver of innovation and sustainable development in the digital age.