This book showcases a collection of papers that present cutting-edge studies, methods, experiments, and applications in various interdisciplinary fields. These fields encompass optimal control, guidance, navigation, game theory, stability, nonlinear dynamics, robotics, sensor fusion, machine learning, and autonomy. The chapters reveal novel studies and methods, providing fresh insights into the field of optimal guidance and control for autonomous systems. The book also covers a wide range of relevant applications, showcasing how optimal guidance and control techniques can be effectively applied in various domains, including mechanical and aerospace engineering. From robotics to sensor fusion and machine learning, the papers explore the practical implications of these techniques and methodologies.