In the dynamic realm of digital agriculture, the integration of big data acquisition platforms has sparked both curiosity and enthusiasm among researchers and agricultural practitioners. This book embarks on a journey to explore the intersection of artificial intelligence and agriculture, focusing on small-unmanned aerial vehicles (UAVs), unmanned ground vehicles (UGVs), edge-AI sensors and the profound impact they have on digital agriculture, particularly in the context of heterogeneous crops, such as walnuts, pomegranates, cotton, etc. For example, lightweight sensors mounted on UAVs, including multispectral and thermal infrared cameras, serve as invaluable tools for capturing high-resolution images. Their enhanced temporal and spatial resolutions, coupled with cost effectiveness and near-real-time data acquisition, position UAVs as an optimal platform for mapping and monitoring crop variability in vast expanses. This combination of data acquisition platforms and advanced analytics generates substantial datasets, necessitating a deep understanding of fractional-order thinking, which is imperative due to the inherent “complexity” and consequent variability within the agricultural process. Much optimism is vested in the field of artificial intelligence, such as machine learning (ML) and computer vision (CV), where the efficient utilization of big data to make it “smart” is of paramount importance in agricultural research. Central to this learning process lies the intricate relationship between plant physiology and optimization methods. The key to the learning process is the plant physiology and optimization method. Crafting an efficient optimization method raises three pivotal questions: 1.) What represents the best approach to optimization? 2.) How can we achieve a more optimal optimization? 3.) Is it possible to demand “more optimal machine learning,” exemplified by deep learning, while minimizing the need for extensive labeled data for digital agriculture? This  book details the  foundations  of  the  plant physiology-informed  machine  learning  (PPIML)  and  the  principle  of  tail  matching (POTM) framework. It is the 9th title of the "Agriculture Automation and Control" book series published by Springer.