Climate change and the increase in environmental stress that it causes has made the need for more stress-tolerant crops to be developed worldwide. This book presents cutting-edge coordinated "omics-CRISPR-nanotechnology" strategies for combating diverse stressors and complicated or multiple stress conditions experienced by crops today. It covers both abiotic and biotic stresses including salinity, temperature, drought, heavy metals, pests and pathogens, and proposes ways to develop stress-tolerant crops with high-yield and high-quality traits through the integration or coordination of three mainstream technologies (multiple omics, CRISPR/Cas9, and nanotechnology). This book is a valuable reference and guide to crucial aspects of methods, applications, and future directions and it opens the door for students and researchers to efficiently view these critical subtopics of plant science and technology and inspire ideas for future experiments. These techniques will help create a more sustainable agriculture in line with the Sustainable Development Goals (SDGs) of the United Nations and the Paris Agreement. The book: · Presents strategies for coordinating multiple omics, CRISPR/Cas9, and nanotechnology techniques for crop improvement · Describes ways to develop abiotic and biotic stress-tolerant crops · Summarizes current achievements in developing climate-smart agriculture