Discovery and Origins.- Discovery.- Embryological Origins and the Identification of Neural Crest Cells.- Delamination, Migration, and Potential.- Evolutionary Origins.- Neural-Crest Derivatives.- Pigment Cells (Chromatophores).- Neuronal Cells and Nervous Systems.- Cartilage Cells and Skeletal Systems.- Teeth and Hearts: The Odontogenic and Cardiac Neural Crests.- Abnormal Development and the Neural Crest.- Neurocristopathies.- NCC Development Revisited in the Context of Birth Defects.