In this issue of PET Clinics, guest editors Drs. Harshad Kulkarni and Abass Alavi bring their considerable expertise to the topic of Theranostics. Tops experts cover key topics such as total-body PET in theranostics: transforming treatment planning and follow-up; FAP-targeted imaging and therapy; theranostics in neuroendocrine neoplasms: integrating imaging, therapy, and dosimetry; theranostics: when targeting imaging leads to a targeted therapy; and much more. Contains 15 relevant, practice-oriented topics including PSMA theranostics in prostate cancer; AI and quantification in theranostics: enabling response prediction and dosimetric accuracy; theranostics in pediatric oncology; building sustainable theranostics programs; PET-based radiation therapy; state-of-the-art radioiodine theranostics of thyroid cancer; and moreProvides in-depth clinical reviews on theranostics, offering actionable insights for clinical practicePresents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews