This book examines the connections between two disparate yet persistently bound thematics -- mobility and intoxication -- and explores their central yet frequently misunderstood role in constructing subjectivity following the 1960s. Emerging from profound mid-twentieth-century changes in how drugs and travel were imagined, the conceptual nexus discussed sheds new light on British and North American responses to sixties counterculture. With readings of Aldous Huxley, William Burroughs, Alex Garland, Hunter S. Thompson, and Robert Sedlack, Banco traces twin arguments, looking at the ways travel is imagined as a disciplinary force acting upon the creative, destabilizing powers of psychedelic intoxication; and exploring the ways drugs help construct travel spaces and practices as, at times, revolutionary, and at other times, neo-colonial. By following a sequence of shifting understandings of drug and travel orthodoxies, this book traverses fraught and irresistibly linked terrains from the late 1950s up to a period marked by international, postmodern tourism. As such, it helps illuminate a world where tourism is continually expanding yet constantly circumscribed, and where illegal drugs are both increasingly unregulated in the global economy and perceived more and more as crucial agents in the construction of human subjectivity.