This textbook challenges the limitations of traditional rational decision-making, arguing that it often fails to address complex, real-world problems. In today's data-driven, rapidly evolving world, decision-makers need a more comprehensive approach. Sensible Decision-Making offers a novel perspective, blending the rigor of logic with the flexibility of human intuition to unlock innovative solutions. While mathematical models provide elegant solutions to well-defined problems, they may not always capture the nuances of human thought and emotion. By integrating systemic and creative thinking, these limitations can be overcome. The knowledge triad synthesis framework, introduced in this book, synthesizes diverse rational, intuitive, and social knowledge sources to empower individuals to make more informed and effective decisions. The book begins by exploring traditional rational decision-making methods, including quantitative analysis of human factors. It then delves into well-established systemic and creative decision-making approaches. Finally, it introduces a novel synthetic decision-making method that reflects the author's innovative vision. Ultimately, this textbook aims to equip readers with the tools and insights needed to navigate the complexities of the twenty-first century. By understanding the principles of synthetic decision-making, readers can become more adaptable, insightful, and sensible decision-makers.