This contributed volume provides a comprehensive and consolidated resource on transition metal-based layered double hydroxides (LDHs). The book bridges the existing knowledge gap by offering an authoritative reference encompassing the latest research, developments, and applications of LDHs. It addresses specific challenges faced by researchers, including the complexities of designing LDHs for various applications, the dispersion of information across multiple sources, and the limited accessibility to up-to-date research. The book explores synthetic methods and functionalization strategies of LDHs while also discussing their various applications in areas such as catalysis, absorption, green chemistry, and/or tissue engineering, among others. It is a valuable resource for graduate students, researchers, and professionals working in the field of transition metal-based layered double hydroxides and materials science.