Applied Cyber Threat Intelligence: From Detection to Disruption is a comprehensive guide for cybersecurity students, analysts, and professionals looking to gain practical, in-demand skills in today’s rapidly evolving digital threat landscape. This book bridges the gap between theoretical knowledge and operational expertise, providing readers with a hands-on approach to Cyber Threat Intelligence (CTI), threat hunting, malware analysis, and open-source investigations. Covering the full CTI lifecycle from intelligence collection and analysis to adversary attribution and takedown, the book offers step-by-step walkthroughs of key tools such as Sysmon-Modular, DeTT&CT, OSSEM, and VirusTotal. Readers will learn how to conduct static and dynamic malware analysis, apply threat frameworks like MITRE ATT&CK and the Diamond Model to perform real-world investigations across surface, deep, and dark web environments. Designed for both classroom use and professional upskilling, the book includes case studies and lab exercises. Whether you're preparing for a cybersecurity role or enhancing your current capabilities, this book equips you with the analytical mindset, technical skills, and practical tools to proactively detect, understand, and respond to cyber threats with confidence and precision.