This book offers several benefits, primarily based on its uniqueness and innovation. It represents the first comprehensive book dedicated solely to negative pressure ventilation (NPV) and Biphasic Cuirass Ventilation (BCV), providing groundbreaking insights into an underrepresented area of respiratory care. The multidisciplinary approach brings together international experts from diverse specialties, fostering a multifaceted understanding of NPV and BCV. The book is well-structured and encompasses a wide variety of topics, including physiological principles, clinical applications, technological advancements, and case studies. The clear and organized format ensures that readers can easily navigate complex concepts and practical applications. This book serves as an educational resource for healthcare professionals, including intensivists, anesthesiologists, pulmonologists, respiratory therapists, biomedical engineers, and healthcare policymakers. It is designed to be both a reference guide and a teaching tool for those new to or experienced in the field. By focusing on NPV and BCV, often overshadowed by positive pressure ventilation methods, this volume bridges a gap in the literature. It highlights the potential benefits and versatility of NPV and BCV in various clinical scenarios, fostering wider adoption and innovation. The main aims and objectives of the book are to increase awareness and understanding of NPV and BCV as viable alternatives or complements to positive pressure ventilation. It provides a comprehensive, structured, and evidence-based resource to enhance the knowledge and skills of healthcare professionals, ultimately aiming to improve outcomes for patients with respiratory conditions.