This handbook addresses how smart operations, management, and healthcare can be used to detect and analyze supply chain problems, business problems, and diseases. It also discusses the underlying methodologies and related security concerns. Handbook of Disruptive Technologies: Operations, Business, Management, and Healthcare provides updated and timely insights, unique approaches or frameworks, practical applications, and case studies. It provides in-depth knowledge of disruptive technologies and applies data analytics to different areas to solve complex situations. The handbook uses data analytics in decision-making and policy framing and identifies practices and applications of disruptive technologies that can assist organizations in gaining a competitive advantage. Valuable insights, innovative approaches, practical applications, and case studies can be found in this handbook as it effectively consolidates and synthesizes information to provide a comprehensive understanding of the subject matter. This book is tailored for researchers, academics, and professionals seeking to deepen their knowledge in the field.