This book mainly studies the methodologies of structural design and construction for highway engineering, which are applicable to the overall control and the precise operation of engineering structures. It explores the method of comprehensive analysis, the simplification of complex problems, and the application of typical engineering tools. In turn, the book presents a number of innovative approaches, e.g. the coordinated control of structural deformation method, the theory of underground engineering balance and stability, and the soft soil foundation treatment of “bumping at the bridgehead.” These methodologies are then illustrated in typical cases and representative problems, explained from a practical standpoint. Examples in special settings are also discussed, e.g. highway construction in Tibet, and rebuilding after the Wenchuan earthquake. The book offers a valuable reference guide for all those whose work involves highway engineering design, construction, management, and scientific research.