This volume gathers essays that focus on the worldliness of science, its inseparable engagement in the major institutional bases of social life: law, market, church, school, and nation. With a chronological span reaching from the Renaissance to Big Science, its topics range from sundials to genetic sequences, from calculating instruments to devices that simulate human behavior, from early cartography to techniques for tracing radioactive fallout on a global scale. The book aims to show readers, with episodes drawn from the span of their modern history, the sciences in action throughout human society.