As the third leading cause of death in the United States, stroke accounts for one in every fifteen deaths and is the major cause of disability in the country. Compiled by a renowned editorial team, this reference bridges the gap between basic science and patient care protocols, and collects 43 expertly written chapters that range from laboratory-based research on animal models to the progression, mechanisms, treatment, and prognosis of diseases such as subarachnoid hemorrhage (SAH), intracerebral hemorrhage (ICH), focal ischemic stroke, and global cerebral ischemia.