The two-volume set LNCS 15701 + 15702 constitutes the proceedings of the 37th International Conference on Advanced Information Systems Engineering, CAiSE 2025, which was held in Vienna, Austria, during June 16–17, 2025. The 35 papers included in the proceedings were carefully reviewed and selected from 229 submissions. They were organized in topical sections as follows:Part I: Modelling with LLM; Security; Sustainability; Chatbots and social networks; process monitoring; IS-development and usage; pre-processing and forecasting; Part II: Comprehension, explanation and recommendation; process discovery; system architecture and privacy; conformance-checking; cloud systems; extending process modelling; ontologies and knowledge graphs.