Vibrational biomedical spectroscopy, near field methods and many aspects of associated biophotonics have advanced significantly in recent years. Diagnostic and prognostic tools based on these new technologies have the potential to revolutionise our clinical systems leading to improved patient outcome, more efficient public services and significant economic savings for healthcare providers and society. This meeting brings together scientists researching vibrational spectroscopy and the development of clinically relevant diagnostic tools to discuss the current challenges and emerging opportunities in this field.