This book explores an important topic: finding and applying alternative means of pathogenic control and treatment via natural sources in the face of increasing numbers of drug-resistant bacteria. It summarizes latest research regarding natural antimicrobial compounds derived from various plant, sponge, and other microbial sources. With collected contributions from international subject experts, it focuses primarily on natural products as a source of bioactive compounds that may be active against multidrug-resistant pathogens, providing an alternative to established antibiotics in controlling infectious diseases.